A Phase 1/2, First-in-Human Study of the Menin-KMT2A (MLL1) Inhibitor Bleximenib in Participants With Acute Leukemia

Investigator: Shilpan Shah

Study Coordinator: Britney Nguyen

Status: Enrolling

ClinicalTrials.gov Number: NCT04811560

Phone: 713.441.0685

Protocol Number: PRO00038342

Description

The purpose of this study is to determine the recommended Phase 2 dose(s) (RP2D[s]) of bleximenib in phase 1 (Part 1 [Dose Escalation] and to determine the safety and tolerability at RP2D in Phase 1 Part 2 (Dose expansion). The purpose of the Phase 2 part of the study is to evaluate the efficacy of bleximenib at the RP2D.
More to Explore