Status: Open Not Enrolling
Investigator: Neal Kleiman
Study Coordinator: Deena Victor
Phone: 713.441.4536
Brief Summary: To evaluate safety and effectiveness of the ACURATE Transfemoral Aortic Valve System for transcatheter aortic valve replacement (TAVR) in subjects with severe native aortic stenosis who are indicated for TAVR. Detailed Descripti ... Read more >
Status: Enrolling
Investigator: Miguel Valderrabano
Study Coordinator: Aneesch Martin
Phone: 713.441.6548
Brief Summary: The objective of this trial is to evaluate the safety and effectiveness of the Amulet LAA occluder compared to NOAC therapy in patients with non-valvular AF at increased risk for ischemic stroke and who are recommended for long-t ... Read more >
Status: Enrolling
Investigator: Sachin Goel
Study Coordinator: Deena Victor
Phone: 713.441.4536
Brief Summary: The objective of this study is to evaluate the preliminary safety and effectiveness of the Cephea Mitral Valve System for the treatment of symptomatic patients with mitral regurgitation = Grade III in whom transcatheter therapy i ... Read more >
Status: Open Not Enrolling
Investigator: Neal Kleiman
Study Coordinator: Deena Victor
Phone: 713.441.4536
The primary objective of the study is to evaluate the safety and effectiveness of the Medtronic CoreValve® System (MCS) in a subset of subjects excluded from the U.S. Extreme Risk Pivotal Trial population due to one or more additional co-morbidi ... Read more >
Status: Open Not Enrolling
Investigator: Miguel Valderrabano
Study Coordinator: Chinwe Ngumezi
Phone: 713.441.6548
Brief Summary: The purpose of the Diamond-AF II study is to establish the safety and effectiveness of the DiamondTemp Ablation System for the treatment of drug refractory, symptomatic persistent atrial fibrillation in patients. Detailed Desc ... Read more >
Status: Enrolling
Investigator: Neal Kleiman
Study Coordinator: Deena Victor
Phone: 713.441.4536
Brief Summary: To establish the safety and effectiveness of the Edwards PASCAL Transcatheter Valve Repair System in patients with degenerative mitral regurgitation (DMR) who have been determined to be at prohibitive risk for mitral valve surger ... Read more >
Status: Enrolling
Investigator: Neal Kleiman
Study Coordinator: Deena Victor
Phone: 713.441.4536
Brief Summary: Obtain safety and effectiveness data to support indication expansion for the Medtronic TAVR System to include patients with moderate, symptomatic AS. Detailed Description: Multi-center, international, prospective, randomized ... Read more >
Status: Enrolling
Investigator: Sachin Goel
Study Coordinator: Tia McGaughy
Phone: 346.238.4576
Brief Summary: The objective of this randomized controlled trial (RCT) is to compare the clinical outcome of MitraClip™ device versus surgical repair in patients with severe primary MR who are at moderate surgical risk and whose mitral valve ha ... Read more >
Status: Open Not Enrolling
Investigator: Neal Kleiman
Study Coordinator: Tia McGaughy
Phone: 346.238.4576
The purpose of the study is to investigate the safety and efficacy of transcatheter aortic valve implantation (TAVI) in patients with severe, symptomatic Aortic Stenosis (AS) at intermediate surgical risk by randomizing patients to either Surgic ... Read more >
Status: Enrolling
Investigator: Michael Reardon
Study Coordinator: Yejide Oyewole
Phone: 346.238.2294
Brief Summary: To collect information about treatment for symptomatic severe Aortic Regurgitation (AR), which affects the aortic valve in the heart. Aortic regurgitation is a condition where aortic valve in the heart does not close tightly and ... Read more >
Status: Enrolling
Investigator: Neal Kleiman
Study Coordinator: Tia McGaughy
Phone: 346.238.4576
Brief Summary: Multi-center, global, prospective, non-randomized, interventional, pre-market trial. All subjects enrolled with receive the study device. Inclusion Criteria: Moderate to severe or severe symptomatic mitral regurgitation Loca ... Read more >
Status: Open Not Enrolling
Investigator: Stephen Little
Study Coordinator: Padmaja Naik
Phone: 713.441.7386
Brief Summary: The primary objective of this trial is to demonstrate the safety and effectiveness of the TriClip device in improving clinical outcomes in symptomatic patients with severe tricuspid regurgitation (TR), who are at intermediate or ... Read more >
Status: Enrolling
Investigator: Sachin Goel
Study Coordinator: Tia McGaughy
Phone: 346.238.4576
Brief Summary: The objective of this early feasibility study is to gain early clinical insight into the performance of the Intrepid transcatheter tricuspid valve replacement (TTVR) system intended for transfemoral access to deliver a self-expan ... Read more >