Status: Enrolling
Investigator: Warren Ellsworth
Study Coordinator: Valentina Villarroel
Phone: 346.238.4384
This is a multicenter registry study to collect utilization, safety, and outcomes data from medical record chart review of nerve reconstruction procedures throughout the body with Avance® Nerve Graft. Addendum 1 (MATCH) establishes a comparat ... Read more >
Status: Open Not Enrolling
Investigator: Bincy Abraham
Study Coordinator: Zinah Rasheed
Phone: 713.363.7536
This is a registry study to evaluate the long-term safety and effectiveness of adalimumab in patients with moderately to severely active UC who are treated as recommended in the product label. ... Read more >
Status: Enrolling
Investigator: Aldona Spiegel
Study Coordinator: Valentina Villarroel
Phone: 346.238.4384
This is a multicenter registry study to collect utilization, safety, and outcomes data from medical record chart review of nerve reconstruction procedures throughout the body with Avance® Nerve Graft. Addendum 1 (MATCH) establishes a comparat ... Read more >
Status: Open Not Enrolling
Investigator: Mahendra Jain
Study Coordinator:
Phone:
This is a randomized, double-blinded, placebo-controlled, two-arm study to evaluate the effectiveness and safety of BIO 300 Oral Suspension (BIO 300) for the mitigation of impaired pulmonary function in 2019 Coronavirus Disease (COVID-19) patien ... Read more >
Status: Enrolling
Investigator: Sandeep Sahay
Study Coordinator: Rosa Barrosa da Costa
Phone: 713.441.5660
The purpose of this study is to investigate acute changes in exercise capacity and exertional symptoms (i.e., dyspnea) post dosing of RT234, as assessed by a cardiopulmonary exercise test (CPET), and 6 -minute walk test (6MWT). In addition, acut ... Read more >
Status: Open Not Enrolling
Investigator: David Victor
Study Coordinator: Beatriz Efron
Phone: 713.363.8890
Study to determine the effect of the investigational drug bezafibrate (BZF) alone and in combination with the investigational drug obeticholic acid (also known as OCA) in patients with Primary Biliary Cholangitis (also known as PBC). ... Read more >
Status: Open Not Enrolling
Investigator: Michael Klebuc
Study Coordinator: Darrel Cleere
Phone: 713.441.6232
This study involves the use of an Investigational Product called NTX-001. It is a product used in the repair of nerve injuries. It is used in the operating room. The main purposes of this study are to 1) see how safe NTX-001 is when used in nerv ... Read more >
Status: Open Not Enrolling
Investigator: Nabil Tariq
Study Coordinator: Nicole Hinton
Phone: 281.755.0796
This study is designed to evaluate the post-operative complications and re-herniations following the use of OviTex in subjects with ventral or inguinal hernias. Up to 160 subjects will participate in the study from up to 20 investigator sites.</ ... Read more >
Status: Enrolling
Investigator: David Victor
Study Coordinator: Beatriz Efron
Phone: 713.363.8890
This Phase 3 study is conducted to evaluate lanifibranor in adults with NASH and liver fibrosis stage 2 or 3. NASH - Nonalcoholic Steatohepatitis - Drug: IVA337 vs Drug: Placebo This Phase 3 study is conducted to evaluate lanifibranor in adu ... Read more >
Status: Enrolling
Investigator: Sandeep Sahay
Study Coordinator: Rosa Barrosa da Costa
Phone: 713.441.5660
Study RIN-PF-305 is designed to evaluate the safety and efficacy of inhaled treprostinil in subjects with progressive pulmonary fibrosis (PPF) over a 52-week period. ... Read more >
Status: Enrolling
Investigator: Sandeep Sahay
Study Coordinator: Cassidy Smith
Phone: 713.441.4106
Study KER-012-A201 is Phase 2, double-blind, randomized, placebo-controlled study to determine the efficacy and safety of KER-012 compared to Placebo in adults with PAH (WHO Group 1 PH) on stable background PAH therapy. The study is divided into ... Read more >
Status: Open Not Enrolling
Investigator: Eamonn Quigley
Study Coordinator: Melissa Whipple
Phone: 713.441.3247
The main aim is to see how TAK-062 works to reduce celiac-related symptoms and improve small intestinal damage due to gluten exposure, in participants with celiac disease (CeD) attempting to maintain a gluten-free diet (GFD) in treated participa ... Read more >
Status: Open Not Enrolling
Investigator: Eamonn Quigley
Study Coordinator: Melissa Whipple
Phone: 713.441.3247
The goal of this clinical trial is to evaluate if the study drug CIN-102 (deudomperidone) can help reduce the symptoms associated with diabetic gastroparesis in adult patients. The main questions it aims to answer are: To evaluate the effi ... Read more >
Status: Open Not Enrolling
Investigator: Bincy Abraham
Study Coordinator: Melissa Whipple
Phone: 713.441.3247
This study is open to adults, aged 18-75 years, with moderate to severe Crohn's disease. The purpose of this study is to find out whether BI 706321 combined with ustekinumab helps people with Crohn's disease. BI 706321 is a medicine being dev ... Read more >
Status: Open Not Enrolling
Investigator: Bincy Abraham
Study Coordinator: Melissa Whipple
Phone: 713.441.3247
This is a multicenter, randomized study to evaluate the long-term efficacy and safety of ABX464 50mg and 25mg administered once daily (QD) as maintenance therapy in subjects with moderately to severely active ulcerative colitis who have inadequa ... Read more >
Status: Enrolling
Investigator: Bincy Abraham
Study Coordinator: Melissa Whipple
Phone: 713.441.3247
This is a multicenter, randomized, placebo controlled study to evaluate the efficacy and safety of ABX464 given at 25 or 50 mg QD in inducing clinical remission in subjects with moderately to severely active ulcerative colitis who have inadequat ... Read more >
Status: Enrolling
Investigator: Sandeep Sahay
Study Coordinator: Nelson Villasmil Hernandez
Phone: 832.970.3187
Study LTI-401 is an open-label, multicenter study which will evaluate the safety and tolerability ofLIQ861 in subjects who have WHO Group 1 & 3 PH. Cohort A will include approximately 60 subjects who have WHO Group 3 Pulmonary Hypertension assoc ... Read more >
Status: Enrolling
Investigator: Bincy Abraham
Study Coordinator: Melissa Whipple
Phone: 713.441.3247
The purpose of this study is to explore the safety, efficacy, effects on quality of life (QOL), and biomarker response of ozanimod in participants with moderate to severely active ulcerative colitis (UC) in clinical practice. ... Read more >
Status: Enrolling
Investigator: Maen Abdelrahim
Study Coordinator: Beatriz Efron
Phone: 713.363.8890
This study will evaluate the efficacy and safety of adjuvant therapy with atezolizumab plus bevacizumab compared with active surveillance in participants with completely resected or ablated hepatocellular carcinoma (HCC) who are at high risk for ... Read more >
Status: Enrolling
Investigator: Raul Sanchez Leon
Study Coordinator: Hira Saleem
Phone: 346.238.0307
Acute kidney injury (AKI) describes a sudden decrease in the glomerular filtration rate and is clinically diagnosed by an increase in serum creatinine and/or a decrease in urine output. An increase in serum creatinine of either = 0.3 mg/dL withi ... Read more >
Status: Enrolling
Investigator: Bincy Abraham
Study Coordinator: Mayyadah Al-Sabbagh
Phone: 346.238.0024
This prospective, non-interventional research registry is designed to study the comparative effectiveness and comparative safety of approved treatments for IBD in a cohort of patients cared for by gastroenterologists across North America. Second ... Read more >
Status: Enrolling
Investigator: Zeenat Safdar
Study Coordinator: Jennifer Lee
Phone: 713.363.7537
This registry will collect data on the strategies used to achieve a diagnosis of Idiopathic Pulmonary Fibrosis (IPF) and Chronic Fibrosing Interstitial Lung Disease with Progressive Phenotype (ILD) and the treatment and management efforts applie ... Read more >
Status: Enrolling
Investigator: Sunil Dacha
Study Coordinator: Zinah Rasheed
Phone: 713.363.7536
The goal of this research is to learn about pyloric sphincter characteristics (measure sphincter pressure, area, and elasticity) in both patients with gastroparesis and without gastroparesis using the endoscopic functional lumen imaging probe (E ... Read more >
Status: Enrolling
Investigator: Joseph Masdeu
Study Coordinator:
Phone:
Schizophrenic and bipolar psychoses are chronic and disabling brain disorders that affect people of all backgrounds. It is thought that in the brain of people with schizophrenic psychosis there is a decreased amount of a receptor known as the N- ... Read more >
Status: Enrolling
Investigator: Joseph Masdeu
Study Coordinator: Nilene Crisci
Phone: 713.441.3771
Some people who have what doctors currently call schizophrenia or bipolar disease may actually have a brain disease caused by auto-antibodies. Auto-antibodies are produced when the normal defense mechanism of the body goes wrong and begins to at ... Read more >
Status: Enrolling
Investigator: Masayoshi Takashima
Study Coordinator: Tariq Syed
Phone: 346.238.6466
This is a Phase 3 Randomized Double-Blind Placebo-Controlled 6-month Parallel-Arm Study to Compare aFixed Dose Combination of AD109 to Placebo in Obstructive Sleep Apnea. ... Read more >
Status: Open Not Enrolling
Investigator: David Victor
Study Coordinator: Beatriz Efron
Phone: 713.363.8890
The goals of this clinical study are to learn more about the study drugs, semaglutide (SEMA) with the fixed-dose combination (FDC) of cilofexor/firsocostat (CILO/FIR), and understand whether they cause fibrosis improvement and Nonalcoholic Steat ... Read more >
Status: Open Not Enrolling
Investigator: Rodney Folz
Study Coordinator: Mayyadah al-Sabbagh
Phone: 346.238.0024
The purpose of this Phase III study is to evaluate the efficacy and safety of tozorakimab300 mg administered subcutaneously (SC) every 2 weeks (Q2W) in adult participants with symptomatic Chronic Obstructive Pulmonary Disease (COPD) with a histo ... Read more >
Status: Open Not Enrolling
Investigator: Zeenat Safdar
Study Coordinator: Royanne Holy
Phone: 713.363.7536
The PHA Registry (PHAR) is a national study about people who have pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). PHAR collects information from people with PAH and CTEPH who are cared for in part ... Read more >
Status: Enrolling
Investigator: Sandeep Sahay
Study Coordinator: Herpreet Sandhu
Phone: 713.441.5660
Study GMS-PH-001 is a multicenter, open-label, non-randomized study to prospectively evaluate screening strategies of pulmonary hypertension (PH) in patients with interstitial lung disease (ILD). In this study, subjects will undergo a broad ran ... Read more >
Status: Enrolling
Investigator: Masayoshi Takashima
Study Coordinator: Tariq Syed
Phone: 346.238.6466
The NEUROMARK RCT Study is a prospective, multicenter, randomized, sham-controlled, single-blinded, superiority trial. ... Read more >
Status: Enrolling
Investigator: Masayoshi Takashima
Study Coordinator: Tariq Syed
Phone: 346.238.6466
The purpose of this study is to determine the safety and effectiveness of CYR-064 in a randomized, double-blinded, placebo-controlled trial to determine the safety and efficacy of CYR064. The study will take approximately 32 weeks which will ... Read more >
Status: Enrolling
Investigator: Christopher Fan
Study Coordinator: Davesia Tenner
Phone: 346.238.4820
This is a prospective observational cohort study designed to collect data on patients who received REBYOTA™ for the prevention of rCDI in the routine care setting. As all data collected for this study are observational, the decision to prescribe ... Read more >
Status: Enrolling
Investigator: Zeenat Safdar
Study Coordinator: Ana Lucia Varon Ocampo
Phone: 713.441.7182
Study ROR-PH-301 is a multicenter, randomized, double-blind, placebo-controlled study. Subjects who meet entry criteria will be randomly allocated 1:1 to receive ralinepag or placebo, in addition to their standard of care or PAH-specific backgro ... Read more >
Status: Enrolling
Investigator: Zeenat Safdar
Study Coordinator: Ana Lucia Varon Ocampo
Phone: 713.441.7182
Study ROR-PH-303 is a multicenter, open-label extension (OLE) study for subjects with WHO Group 1 PAH who have participated in another Phase 2 or Phase 3 study of ralinepag and who qualify for entry based upon participation in the prior study. S ... Read more >
Status: Open Not Enrolling
Investigator: David Victor
Study Coordinator: Beatriz Efron
Phone: 713.363.8890
Semaglutide is a medicine studied in patients with NASH. Semaglutide is a well-known medicine, which is already used by doctors to treat type 2 diabetes in many countries. Participants will either get semaglutide or a dummy medicine - which t ... Read more >
Status: Open Not Enrolling
Investigator: Bincy Abraham
Study Coordinator: Melissa Whipple
Phone: 713.441.3247
Transmural healing (TMH) is recognized as a potentially important measure of Crohn's disease (CD) activity but not a formal target. Observational studies suggest that TMH may be associated with better long-term outcomes. The study will evaluate ... Read more >
Status: Open Not Enrolling
Investigator: Laila Tabatabai
Study Coordinator: Melissa Whipple
Phone: 713.441.3247
The XLH-DMP is a global, prospective, multicenter, longitudinal, long-term outcomes program for subjects on or off any treatment designed to characterize XLH disease presentation and progression, assess long-term safety and effectiveness of buro ... Read more >