William Zoghbi Download Headshot

William A. Zoghbi, MD, MACC, FAHA, FASE

  • Houston Methodist cardiologist
  • Chair, Houston Methodist Hospital department of cardiology
  • Elkins Family Distinguished Chair in Cardiac Health at the Houston Methodist DeBakey Heart & Vascular Center
  • Past President, American College of Cardiology
  • Professor of medicine, Weill Cornell Medical College
Media Contact: Daniel Brown , 832.667.5849

William A. Zoghbi, MD, MACC, FAHA, FASE

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Media Contact: Daniel Brown , 832.667.5849

Areas of Expertise

  • Cardiac imaging
  • Echocardiography 
  • Heart failure
  • Myocardial hibernation
  • Valvular function 
  • Ventricular function 

Credentials

BOARD CERTIFICATION
Cardiovascular Disease, Subspecialty Certification in Echocardiography
MEDICAL SCHOOL
Meharry Medical College School of Medicine | 1979
INTERNSHIP
University of Texas Medical Branch Hospital - Internal Medicine - Galveston, TX | 1980
RESIDENCY
Baylor College of Medicine - Internal Medicine - Houston | 1980
FELLOWSHIP
Baylor College of Medicine - Cardiology - Houston | 1985

Publications

High-Gradient “Moderate” Aortic Stenosis: Is it Moderate or Severe?
Zoghbi, WA 2025, , JACC: Cardiovascular Imaging, vol. 18, no. 2, pp. 177-179. https://doi.org/10.1016/j.jcmg.2024.10.013

The continuity equation is superior to the pressure half-time method in calcific mitral stenosis: a comparison with cardiac catheterization
Saad, JM, O’Sullivan, S, Sabbagh, AE & Zoghbi, WA 2025, , European Heart Journal Cardiovascular Imaging, vol. 26, no. 2, pp. 313-315. https://doi.org/10.1093/ehjci/jeae253

Beta-Blockers After PCI for Stable Coronary Artery Disease and Preserved Left Ventricular Ejection Fraction
Khan, SU, Akbar, UA, Khan, MS, Patel, KV, Nadeem, A, Thakkar, S, Arshad, HB, Virani, SS, Nasir, K, Goel, S, Shah, AR, Zoghbi, W & Kleiman, N 2025, , JACC: Advances, vol. 4, no. 2, 101566, pp. 101566. https://doi.org/10.1016/j.jacadv.2024.101566

Classification of Deformable Smooth Shapes Through Geodesic Flows of Diffeomorphisms
Dabirian, H, Sultamuratov, R, Herring, J, El Tallawi, C, Zoghbi, W, Mang, A & Azencott, R 2024, , Journal of Mathematical Imaging and Vision, vol. 66, no. 6, pp. 1033-1059. https://doi.org/10.1007/s10851-024-01211-z

Impact of systolic dominant pulmonary venous flow morphology on outcomes after mitral transcatheter edge-to-edge repair
Samimi, S, Hatab, T, Bou Chaaya, R, Kharsa, C, Qamar, F, Faza, N, Little, SH, Atkins, MD, Reardon, MJ, Kleiman, NS, Nagueh, SF, Zoghbi, WA, Zaid, S & Goel, SS 2024, , Catheterization and Cardiovascular Interventions, vol. 104, no. 5, pp. 1027-1036. https://doi.org/10.1002/ccd.31232

Impact of Residual Transmitral Mean Pressure Gradient on Outcomes After Mitral Transcatheter Edge-to-Edge Repair
Sammour, YM, Bou Chaaya, RG, Hatab, T, Zaid, S, Aoun, J, Wessly, P, Kharsa, C, Zoghbi, WA, Nagueh, S, Atkins, MD, Reardon, MJ, Faza, N, Little, SH, Kleiman, NS & Goel, SS 2024, , JACC: Advances, vol. 3, no. 10, 101227, pp. 101227. https://doi.org/10.1016/j.jacadv.2024.101227

Impact of Left Atrial Pressure on Outcomes after Mitral Transcatheter Edge-to-Edge Repair
Sammour, YM, Bou Chaaya, RG, Hatab, T, Zaid, S, Aoun, J, Makram, OM, Wessly, P, Samimi, S, Nagueh, SF, Zoghbi, WA, Atkins, MD, Reardon, MJ, Faza, N, Little, SH, Kleiman, N & Goel, S 2024, , Circulation: Cardiovascular Interventions, vol. 17, no. 9, pp. e014055. https://doi.org/10.1161/CIRCINTERVENTIONS.124.014055

Atrial cardiomyopathy revisited - evolution of a concept: a clinical consensus statement of the European Heart Rhythm Association (EHRA) of the ESC, the Heart Rhythm Society (HRS), the Asian Pacific Heart Rhythm Society (APHRS), and the Latin American Heart Rhythm Society (LAHRS)
Goette, A, Corradi, D, Dobrev, D, Aguinaga, L, Cabrera, JA, Chugh, SS, De Groot, JR, Soulat-Dufour, L, Fenelon, G, Hatem, SN, Jalife, J, Lin, YJ, Lip, GYH, Marcus, GM, Murray, KT, Pak, HN, Schotten, U, Takahashi, N, Yamaguchi, T, Zoghbi, WA, Nattel, S, Mont, L, Akar, JG, Akoum, N, Althoff, T, Diaz, JC, Guichard, JB, Jadidi, A, Kalman, J, Lim, H & Teixeira, RA 2024, , Europace, vol. 26, no. 9, euae204. https://doi.org/10.1093/europace/euae204

Impact of Left Atrial Pressure on Outcomes after Mitral Transcatheter Edge-to-Edge Repair
Sammour, YM, Bou Chaaya, RG, Hatab, T, Zaid, S, Aoun, J, Makram, OM, Wessly, P, Samimi, S, Nagueh, SF, Zoghbi, WA, Atkins, MD, Reardon, MJ, Faza, N, Little, SH, Kleiman, NS & Goel, SS 2024, , Circulation. Cardiovascular interventions, vol. 17, no. 9, pp. e014055. https://doi.org/10.1161/CIRCINTERVENTIONS.124.014055

Myocardial Blood Flow Reserve, Microvascular Coronary Health, and Myocardial Remodeling in Patients With Aortic Stenosis
Alahdab, F, Ahmed, AI, Nayfeh, M, Han, Y, Abdelkarim, O, Alfawara, MS, Little, SH, Reardon, MJ, Faza, NN, Goel, SS, Alkhouli, M, Zoghbi, W & Al-Mallah, MH 2024, , Journal of the American Heart Association, vol. 13, no. 11, e033447, pp. e033447. https://doi.org/10.1161/JAHA.123.033447

Houston Methodist cardiovascular learning health system (CVD-LHS) registry: Methods for development and implementation of an automated electronic medical record-based registry using an informatics framework approach
Nasir, K, Gullapelli, R, Nicolas, JC, Bose, B, Nwana, N, Butt, SA, Shahid, I, Cainzos-Achirica, M, Patel, KV, Bhimaraj, A, Javed, Z, Andrieni, J, Al-Kindi, S, Jones, SL & Zoghbi, WA 2024, , American Journal of Preventive Cardiology, vol. 18, 100678, pp. 100678. https://doi.org/10.1016/j.ajpc.2024.100678, https://doi.org/10.1016/j.ajpc.2024.100678

Houston Methodist cardiovascular learning health system (CVD-LHS) registry: Methods for development and implementation of an automated electronic medical record-based registry using an informatics framework approach
Nasir, K, Gullapelli, R, Nicolas, JC, Bose, B, Nwana, N, Butt, SA, Shahid, I, Cainzos-Achirica, M, Patel, KV, Bhimaraj, A, Javed, Z, Andrieni, J, Al-Kindi, S, Jones, SL & Zoghbi, WA 2024, , American Journal of Preventive Cardiology, vol. 18, 100678. https://doi.org/10.1016/j.ajpc.2024.100678

Prognostic Value of Right Ventricular Afterload in Patients Undergoing Mitral Transcatheter Edge-to-Edge Repair
Bou Chaaya, RG, Hatab, T, Samimi, S, Qamar, F, Kharsa, C, Aoun, J, Faza, N, Little, SH, Atkins, MD, Reardon, MJ, Kleiman, N, Nagueh, SF, Zoghbi, WA, Guha, A, Zaid, S & Goel, S 2024, , Journal of the American Heart Association, vol. 13, no. 8, e033510. https://doi.org/10.1161/JAHA.123.033510

Prognostic Interplay Between Exercise Capacity and PET-Derived Myocardial Flow Reserve: FIT-PET Study
Ahmed, AI, Al Rifai, M, Alahdab, F, Alfawara, MS, Han, Y, Nayfeh, M, Mahmarian, JJ, Nabi, F, Soliman, A, Patel, K, Zoghbi, WA & Al-Mallah, MH 2024, , JACC: Cardiovascular Imaging, vol. 17, no. 4, pp. 460-462. https://doi.org/10.1016/j.jcmg.2023.11.002

Intraprocedural Doppler and Invasive Hemodynamic Profiling Predict Clinical Outcomes After Mitral TEER
Zaid, S, Wessly, P, Hatab, T, Faza, N, Little, SH, Atkins, MD, Reardon, MJ, Kleiman, NS, Zoghbi, WA & Goel, SS 2024, , JACC: Cardiovascular Imaging, vol. 17, no. 4, pp. 454-456. https://doi.org/10.1016/j.jcmg.2023.10.013

Echocardiographic Profiling Predicts Clinical Outcomes After Mitral Transcatheter Edge-to-Edge Repair
Hatab, T, Samimi, S, Chaaya, RGB, Qamar, F, Kharsa, C, Wessly, P, Faza, N, Little, SH, Atkins, MD, Reardon, MJ, Kleiman, NS, Zoghbi, WA, Nagueh, SF, Zaid, S & Goel, SS 2024, , Journal of the American Heart Association, vol. 13, no. 5, e032784, pp. e032784. https://doi.org/10.1161/JAHA.123.032784

Characteristics and Outcomes of Patients Ineligible for Tricuspid Transcatheter Edge-to-Edge Repair
Hatab, T, Bou Chaaya, RG, Samimi, S, Qamar, F, Faza, N, Little, SH, Reardon, MJ, Kleiman, NS, Zoghbi, WA, Guha, A, Zaid, S & Goel, SS 2024, , Structural Heart, vol. 8, no. 2, 100235, pp. 100235. https://doi.org/10.1016/j.shj.2023.100235

Guidelines for the Evaluation of Prosthetic Valve Function With Cardiovascular Imaging: A Report From the American Society of Echocardiography Developed in Collaboration With the Society for Cardiovascular Magnetic Resonance and the Society of Cardiovascular Computed Tomography
Zoghbi, WA, Jone, PN, Chamsi-Pasha, MA, Chen, T, Collins, KA, Desai, MY, Grayburn, P, Groves, DW, Hahn, RT, Little, SH, Kruse, E, Sanborn, D, Shah, SB, Sugeng, L, Swaminathan, M, Thaden, J, Thavendiranathan, P, Tsang, W, Weir-McCall, JR & Gill, E 2024, , Journal of the American Society of Echocardiography, vol. 37, no. 1, pp. 2-63. https://doi.org/10.1016/j.echo.2023.10.004


Building a Novel Artificial Intelligence–Driven Echocardiographic Data Pipeline: Findings From a Large Learning Health System
Bose, B, Butt, SA, Arshad, HB, Nicolas, CC, Gullapelli, R, Nwana, N, Javed, Z, Shahid, I, Pournazari, P, Patel, KV, Chamsi Pasha, MA, Little, SH, Faza, NS, Jones, S, Cainzos, MA, Al-Kindi, S, Saad, JM, Zoghbi, W, Nagueh, SF & Nasir, K 2024, , Journal of the American Society of Echocardiography, vol. 37, no. 9, pp. 916-918. https://doi.org/10.1016/j.echo.2024.05.018

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