Sherif Nagueh, MD

The Levant Foundation Chair in Cardiovascular Diseases, DeBakey Heart & Vascular Center
Professor of Cardiology, Academic Institute
Full Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Biography

In 1996, Dr. Nagueh joined the Section of Cardiology in the Department of Medicine at the Baylor College of Medicine as an Assistant Professor. He was promoted in 2001 to an Associate Professor, and became the T.L.L Temple/William H. Spencer, MD Chair in Clinical Cardiology there in 2004. Dr. Nagueh assumed his positions at Houston Methodist in 2005.

Description of Research

Dr. Nagueh´s research career has been in the field of echocardiography. He has authored or co-authored over 100 manuscripts in peer reviewed journals and four book chapters. His research interest has been in the evaluation of diastolic function with tissue Doppler and its application in hypertrophic cardiomyopathy, particularly in patients undergoing alcohol septal ablation.

Areas Of Expertise

Alcohol septal ablation Echocardiography Diastolic function Doppler
Education & Training

Residency, Baylor College of Medicine
MD, University of Cairo
Active Clinical Trials

HCMR - Novel

NCT01915615


AC-058B201 Echocardiographic Ancillary Study

N/A

Publications

Safety and Efficacy of Metabolic Modulation With Ninerafaxstat in Patients With Nonobstructive Hypertrophic Cardiomyopathy
Maron, MS, Mahmod, M, Abd Samat, AH, Choudhury, L, Massera, D, Phelan, DMJ, Cresci, S, Martinez, MW, Masri, A, Abraham, TP, Adler, E, Wever-Pinzon, O, Nagueh, SF, Lewis, GD, Chamberlin, P, Patel, J, Yavari, A, Dehbi, HM, Sarwar, R, Raman, B, Valkovic, L, Neubauer, S, Udelson, JE & Watkins, H 2024, , Journal of the American College of Cardiology, vol. 83, no. 21, pp. 2037-2048. https://doi.org/10.1016/j.jacc.2024.03.387

Left Atrial Conduit Volume Provides Insights into Left Ventricular Diastolic Function
Nagueh, SF 2024, , Circulation: Cardiovascular Imaging, vol. 17, no. 5, pp. E016896. https://doi.org/10.1161/CIRCIMAGING.124.016896

Prognostic Value of Right Ventricular Afterload in Patients Undergoing Mitral Transcatheter Edge-to-Edge Repair
Bou Chaaya, RG, Hatab, T, Samimi, S, Qamar, F, Kharsa, C, Aoun, J, Faza, N, Little, SH, Atkins, MD, Reardon, MJ, Kleiman, N, Nagueh, SF, Zoghbi, WA, Guha, A, Zaid, S & Goel, S 2024, , Journal of the American Heart Association, vol. 13, no. 8, e033510. https://doi.org/10.1161/JAHA.123.033510

Echocardiographic Profiling Predicts Clinical Outcomes After Mitral Transcatheter Edge-to-Edge Repair
Hatab, T, Samimi, S, Chaaya, RGB, Qamar, F, Kharsa, C, Wessly, P, Faza, N, Little, SH, Atkins, MD, Reardon, MJ, Kleiman, NS, Zoghbi, WA, Nagueh, SF, Zaid, S & Goel, SS 2024, , Journal of the American Heart Association, vol. 13, no. 5, e032784, pp. e032784. https://doi.org/10.1161/JAHA.123.032784

Noninvasive Prediction of Pulmonary Capillary Wedge Pressure in Patients With Normal Left Ventricular Ejection Fraction: Comparison of Cardiac Magnetic Resonance With Comprehensive Echocardiography
Rahi, W, Hussain, I, Quinones, MA, Zoghbi, WA, Shah, DJ & Nagueh, SF 2024, , Journal of the American Society of Echocardiography, vol. 37, no. 5, pp. 486-494. https://doi.org/10.1016/j.echo.2024.02.001

Efficacy and Safety of Aficamten in Symptomatic Nonobstructive Hypertrophic Cardiomyopathy: Results From the REDWOOD-HCM Trial, Cohort 4
REDWOOD-HCM Investigators 2024, , Journal of Cardiac Failure. https://doi.org/10.1016/j.cardfail.2024.02.020

Validation of Noninvasive Left Atrial Stiffness Against Left Atrial Operating Chamber Stiffness by Cardiac Catheterization
Mathias, IS, Rahi, W, Ramos, A, Na, J, Angulo, C, Rothstein, P, Lador, A, Schurmann, P, Dave, A, Valderrabano, M & Nagueh, SF 2024, , JACC: Cardiovascular Imaging. https://doi.org/10.1016/j.jcmg.2024.03.004

Early Observations on Effects of Mavacamten on Left Atrial Function in Obstructive Hypertrophic Cardiomyopathy Patients
Wessly, P, Lazzara, GE, Buergler, JM & Nagueh, SF 2023, , JACC: Cardiovascular Imaging, vol. 16, no. 12, pp. 1633-1634. https://doi.org/10.1016/j.jcmg.2023.06.008

Accuracy of Clinical Evaluation and Chest X-ray for HFpEF Diagnosis: Comparison Against Right Heart Catheterization
Rahi, W, Hussain, I, Nguyen, DT, Graviss, EA, Quinones, MA & Nagueh, SF 2023, , American Journal of Cardiology, vol. 206, pp. 219-220. https://doi.org/10.1016/j.amjcard.2023.08.112

Accuracy of Clinical Evaluation and Chest X-ray for HFpEF Diagnosis: Comparison Against Right Heart Catheterization
Rahi, W, Hussain, I, Nguyen, DT, Graviss, EA, Quinones, MA & Nagueh, SF 2023, , The American Journal of Cardiology, vol. 206, pp. 219-220. https://doi.org/10.1016/j.amjcard.2023.08.112

American Society of Echocardiography COVID-19 Statement Update: Lessons Learned and Preparation for Future Pandemics
Kirkpatrick, JN, Swaminathan, M, Adedipe, A, Garcia-Sayan, E, Hung, J, Kelly, N, Kort, S, Nagueh, S, Poh, KK, Sarwal, A, Strachan, GM, Topilsky, Y, West, C & Wiener, DH 2023, , Journal of the American Society of Echocardiography, vol. 36, no. 11, pp. 1127-1139. https://doi.org/10.1016/j.echo.2023.08.020

Imaging for implementation of heart failure guidelines
Nagueh, SF, Nabi, F, Chang, SM, Al-Mallah, M, Shah, DJ & Bhimaraj, A 2023, , European Heart Journal Cardiovascular Imaging, vol. 24, no. 10, pp. 1283-1292. https://doi.org/10.1093/ehjci/jead163

Echocardiographic Evaluation of Diastolic Function in Special Populations
Chan, N, Wang, TKM, Anthony, C, Hassan, OA, Chetrit, M, Dillenbeck, A, Smiseth, OA, Nagueh, SF & Klein, AL 2023, , American Journal of Cardiology, vol. 202, pp. 131-143. https://doi.org/10.1016/j.amjcard.2023.05.032

Editorial introductions
Nagueh, S, Verma, S & Yanagawa, B 2023, , Current Opinion in Cardiology, vol. 38, no. 5, pp. V. https://doi.org/10.1097/HCO.0000000000001072

A Vision for the Future of Quality in Echocardiographic Reporting: The American Society of Echocardiography ImageGuideEcho Registry, Current and Future States
Nagueh, SF, Klein, AL, Scherrer-Crosbie, M, Fine, NM, Kirkpatrick, JN, Forsha, DE, Nicoara, A, Mackensen, GB, Tilkemeier, PL, Doukky, R, Cheema, B, Adusumalli, S, Hill, JC, Tanguturi, VK, Ouyang, D, Bdoyan, SB & Strom, JB 2023, , Journal of the American Society of Echocardiography, vol. 36, no. 8, pp. 805-811. https://doi.org/10.1016/j.echo.2023.05.001

Left Atrial Strain for Assessment of Left Ventricular Diastolic Function: Focus on Populations With Normal LVEF
Nagueh, SF & Khan, SU 2023, , JACC: Cardiovascular Imaging, vol. 16, no. 5, pp. 691-707. https://doi.org/10.1016/j.jcmg.2022.10.011

Noninvasive Measurement of Left Atrial Stiffness in Patients With Heart Failure and Preserved Ejection Fraction
Nagueh, SF 2023, , JACC: Cardiovascular Imaging, vol. 16, no. 4, pp. 446-449. https://doi.org/10.1016/j.jcmg.2022.12.003

Phase 2 Study of Aficamten in Patients With Obstructive Hypertrophic Cardiomyopathy
REDWOOD-HCM Steering Committee and Investigators 2023, , Journal of the American College of Cardiology, vol. 81, no. 1, pp. 34-45. https://doi.org/10.1016/j.jacc.2022.10.020

Cardiac Involvement in Fabry Disease and the Role of Multimodality Imaging in Diagnosis and Disease Monitoring
Umer, M, Motwani, M, Jefferies, JL, Nagueh, SF & Kalra, DK 2023, , Current Problems in Cardiology, vol. 48, no. 1, 101439, pp. 101439. https://doi.org/10.1016/j.cpcardiol.2022.101439

Left Ventricular Diastolic Dysfunction: Diagnostic and Prognostic Perspectives
Nagueh, SF 2023, , Journal of the American Society of Echocardiography, vol. 36, no. 3, pp. 307-309. https://doi.org/10.1016/j.echo.2022.12.015