Rodrigo de Paula Baptista

Rodrigo de Paula Baptista, PhD

Assistant Research Professor of Medicine, Academic Institute
Assistant Research Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Areas Of Expertise

Bioinformatics Genomics microbiology Trancriptomics Parasitology evolution phylogenetics
Education & Training

PhD, Universidade Federal de Minas Gerais
Postdoctoral Fellowship, Universidade Federal de Minas Gerais
BSc, Universidade Fumec
Postdoctoral Associate, University of Georgia
Publications

Comparative genomics of Giardia duodenalis sub-assemblage AI beaver (Be-2) and human (WB-C6) strains show remarkable homozygosity, sequence similarity, and conservation of VSP genes
de Paula Baptista, R, Tucker, MS, Valente, MJ, Srivastava, SK, Chehab, N, Li, A, Shaik, JS, Ramirez, JD, Rosenthal, BM & Khan, A 2024, , Scientific Reports, vol. 14, no. 1, 13582. https://doi.org/10.1038/s41598-024-63783-5

Genomic and virulence analysis of in vitro cultured Cryptosporidium parvum
Yarlett, N, Morada, M, Schaefer, DA, Ackman, K, Carranza, E, Baptista, RDP, Riggs, MW & Kissinger, J 2024, , PLoS pathogens, vol. 20, no. 2, e1011992, pp. e1011992. https://doi.org/10.1371/journal.ppat.1011992

A new chromosome-level genome assembly and annotation of Cryptosporidium meleagridis.
Penumarthi, LR, Baptista, RP, Beaudry, MS, Glenn, TC & Kissinger, JC 2024, , bioRxiv. https://doi.org/10.1101/2024.02.16.580748

"Evaluating the Benefits and Limits of Multiple Displacement Amplification with Whole-Genome Oxford Nanopore Sequencing"
Dadzie, FA, Beaudry, MS, Deyanov, A, Slanis, H, Duong, MQ, Turner, R, Khan, A, Arias, CA, Kissinger, JC, Glenn, TC & de Paula Baptista, R 2024, , bioRxiv. https://doi.org/10.1101/2024.02.09.579537

Inherently Reduced Expression of ASC Restricts Caspase-1 Processing in Hepatocytes and Promotes Plasmodium Infection
Marques-Da-Silva, C, Schmidt-Silva, C, Baptista, RP & Kurup, SP 2024, , Journal of Immunology, vol. 212, no. 4, pp. 596-606. https://doi.org/10.4049/jimmunol.2300440

Genomic and virulence analysis of in vitro cultured Cryptosporidium parvum
Yarlett, N, Morada, M, Schaefer, DA, Ackman, K, Carranza, E, Baptista, RDP, Riggs, MW & Kissinger, J 2024, , PLoS pathogens, vol. 20, no. 2, e1011992. https://doi.org/10.1371/journal.ppat.1011992

Cefiderocol heteroresistance associated with mutations in TonB-dependent receptor genes in Pseudomonas aeruginosa of clinical origin.
Egge, SL, Rizvi, SA, Simar, SR, Alcalde, M, Martinez, JRW, Hanson, BM, Dinh, AQ, Baptista, RP, Tran, TT, Shelburne, SA, Munita, JM, Arias, CA, Hakki, M & Miller, WR 2024, , bioRxiv. https://doi.org/10.1101/2024.01.30.578008

Genetic crosses within and between species of Cryptosporidium
Shaw, S, Cohn, IS, Baptista, RP, Xia, G, Melillo, B, Agyabeng-Dadzie, F, Kissinger, JC & Striepen, B 2024, , Proceedings of the National Academy of Sciences of the United States of America, vol. 121, no. 1, e2313210120. https://doi.org/10.1073/pnas.2313210120

Genetic crosses within and between species of Cryptosporidium
Shaw, S, Cohn, IS, Baptista, RP, Xia, G, Melillo, B, Agyabeng-Dadzie, F, Kissinger, JC & Striepen, B 2024, , Proceedings of the National Academy of Sciences of the United States of America, vol. 121, no. 1, e2313210120. https://doi.org/10.1073/pnas.2313210120

The emergence of cefiderocol resistance in Pseudomonas aeruginosa from a heteroresistant isolate during prolonged therapy
Teran, N, Egge, SL, Phe, K, Baptista, RP, Tam, VH & Miller, WR 2024, , Antimicrobial Agents and Chemotherapy, vol. 68, no. 1. https://doi.org/10.1128/aac.01009-23

The first Cryptosporidium meeting: a concerted effort to fight cryptosporidiosis
van Voorhis, W, Siwila, J, Kissinger, JC, Vásquez, NB, Robinson, G, Baptista, R, Khan, A, Guérin, A, Chang, YW, Noor, Z, Marzook, NB, Vinayak, S, Arnold, S, Marie, C, Choy, RKM, Pawlowic, MC & Jumani, RS 2024, , Trends in Parasitology, vol. 40, no. 6, pp. 431-438. https://doi.org/10.1016/j.pt.2024.04.005

Inherently Reduced Expression of ASC Restricts Caspase-1 Processing in Hepatocytes and Promotes Plasmodium Infection
Marques-Da-Silva, C, Schmidt-Silva, C, Baptista, RP & Kurup, SP 2024, , Journal of immunology (Baltimore, Md. : 1950), vol. 212, no. 4, pp. 596-606. https://doi.org/10.4049/jimmunol.2300440

The emergence of cefiderocol resistance in Pseudomonas aeruginosa from a heteroresistant isolate during prolonged therapy.
Teran, N, Egge, SL, Phe, K, Baptista, RP, Tam, VH & Miller, WR 2024, , Antimicrobial Agents and Chemotherapy, vol. 68, no. 1, pp. e0100923. https://doi.org/10.1128/aac.01009-23

Membrane Phenotypic, Metabolic and Genotypic Adaptations of Streptococcus oralis Strains Destined to Rapidly Develop Stable, High-Level Daptomycin Resistance during Daptomycin Exposures
Mishra, NN, de Paula Baptista, R, Tran, TT, Lapitan, CK, Garcia-de-la-Maria, C, Miró, JM, Proctor, RA & Bayer, AS 2023, , Antibiotics, vol. 12, no. 7, 1083. https://doi.org/10.3390/antibiotics12071083

Membrane Phenotypic, Metabolic and Genotypic Adaptations of Streptococcus oralis Strains Destined to Rapidly Develop Stable, High-Level Daptomycin Resistance during Daptomycin Exposures
Mishra, NN, de Paula Baptista, R, Tran, TT, Lapitan, CK, Garcia-de-la-Maria, C, Miró, JM, Proctor, RA & Bayer, AS 2023, , Antibiotics, vol. 12, no. 7, 1083. https://doi.org/10.3390/antibiotics12071083, https://doi.org/10.3390/antibiotics12071083

New T2T assembly of Cryptosporidium parvum IOWA annotated with reference genome gene identifiers.
de Paula Baptista, R, Xiao, R, Li, Y, Glenn, TC & Kissinger, JC 2023, , bioRxiv. https://doi.org/10.1101/2023.06.13.544219

An X-Domain Phosphoinositide Phospholipase C (PI-PLC-like) of Trypanosoma brucei Has a Surface Localization and Is Essential for Proliferation.
Negrão, NW, Crowe, LP, Mantilla, BS, Baptista, RP, King-Keller, S, Huang, G & Docampo, R 2023, , Pathogens, vol. 12, no. 3, 386. https://doi.org/10.3390/pathogens12030386

An X-Domain Phosphoinositide Phospholipase C (PI-PLC-like) of Trypanosoma brucei Has a Surface Localization and Is Essential for Proliferation
Negrão, NW, Crowe, LP, Mantilla, BS, Baptista, RP, King-Keller, S, Huang, G & Docampo, R 2023, , Pathogens, vol. 12, no. 3, 386. https://doi.org/10.3390/pathogens12030386

AIM2 sensors mediate immunity to Plasmodium infection in hepatocytes
Marques-Da-Silva, C, Poudel, B, Baptista, RP, Peissig, K, Hancox, LS, Shiau, JC, Pewe, LL, Shears, MJ, Kanneganti, TD, Sinnis, P, Kyle, DE, Gurung, P, Harty, JT & Kurup, SP 2023, , Proceedings of the National Academy of Sciences of the United States of America, vol. 120, no. 2, e2210181120. https://doi.org/10.1073/pnas.2210181120

Epidemiologic investigation and genetic characterization of canine respiratory coronavirus in the Southeastern United States
De Luca, E, Álvarez-Narváez, S, Baptista, RP, Maboni, G, Blas-Machado, U & Sanchez, S 2024, , Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, vol. 36, no. 1, pp. 46-55. https://doi.org/10.1177/10406387231213662

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