Belen Pascual

Belen Pascual, PhD

Associate Research Professor of Neurology, Academic Institute
Associate Research Member, Research Institute
Co-Director, Neuroimaging, Nantz National Alzheimer Center
Houston Methodist
Weill Cornell Medical College


Neuroimaging Research Lab


Areas Of Expertise

Neuroimaging Neuropsychology Alzheimer's Disease Neuroinflammation Frontotemporal Degeneration Neurodegenerative Diseases Brain Functional Organization Memory Disorders Language Architecture
Active Clinical Trials

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

N/A

Publications

Anterior insula is more vulnerable than posterior insula to TDP-43 pathology in common dementias and ALS
Lochner, RH, Arumanayagam, AS, Powell, SZ, Masdeu, JC, Pascual, B & Cykowski, MD 2024, , Journal of Neuropathology and Experimental Neurology, vol. 83, no. 5, pp. 307-317. https://doi.org/10.1093/jnen/nlae027

Research Participants' Perspectives on Precision Diagnostics for Alzheimer's Disease
Smith, HS, Robinson, JO, Levchenko, A, Pereira, S, Pascual, B, Bradbury, K, Arbones, V, Fong, J, Shulman, JM, Mcguire, AL & Masdeu, J 2024, , Journal of Alzheimers Disease, vol. 97, no. 3, pp. 1261-1274. https://doi.org/10.3233/JAD-230609

Reliability and Validity of Smartphone Cognitive Testing for Frontotemporal Lobar Degeneration
Staffaroni, AM, Clark, AL, Taylor, JC, Heuer, HW, Sanderson-Cimino, M, Wise, AB, Dhanam, S, Cobigo, Y, Wolf, A, Manoochehri, M, Forsberg, L, Mester, C, Rankin, KP, Appleby, BS, Bayram, E, Bozoki, A, Clark, D, Darby, RR, Domoto-Reilly, K, Fields, JA, Galasko, D, Geschwind, D, Ghoshal, N, Graff-Radford, N, Grossman, M, Hsiung, GY, Huey, ED, Jones, DT, Lapid, MI, Litvan, I, Masdeu, JC, Massimo, L, Mendez, MF, Miyagawa, T, Pascual, B, Pressman, P, Ramanan, VK, Ramos, EM, Rascovsky, K, Roberson, ED, Tartaglia, MC, Wong, B, Miller, BL, Kornak, J, Kremers, W, Hassenstab, J, Kramer, JH, Boeve, BF, Rosen, HJ & Boxer, AL 2024, , JAMA Network Open, pp. E244266. https://doi.org/10.1001/jamanetworkopen.2024.4266

A phase 1 open-label pilot study of low-dose interleukine-2 immunotherapy in patients with Alzheimer's disease
Faridar, A, Eid, AM, Thome, AD, Zhao, W, Beers, DR, Pascual, MB, Nakawah, MO, Roman, GC, Davis, CS, Grundman, M, Masdeu, JC & Appel, SH 2023, , Translational Neurodegeneration, vol. 12, no. 1, pp. 54. https://doi.org/10.1186/s40035-023-00387-5

A phase 1 open-label pilot study of low-dose interleukine-2 immunotherapy in patients with Alzheimer’s disease
Faridar, A, Eid, AM, Thome, AD, Zhao, W, Beers, DR, Pascual, MB, Nakawah, MO, Roman, GC, Davis, CS, Grundman, M, Masdeu, JC & Appel, SH 2023, , Translational Neurodegeneration, vol. 12, no. 1, 54, pp. 54. https://doi.org/10.1186/s40035-023-00387-5

The Self-Administered Screening Questionnaire for Parkinson's Disease-Associated Psychosis (SASPAP)
Koneru, V, Espay, AJ, Cole, AJ, Weintraub, D, Crist, K, Pascual, MB & Ondo, WG 2023, , Movement disorders : official journal of the Movement Disorder Society, vol. 38, no. 11, pp. 1982-1987. https://doi.org/10.1002/mds.29627

Plasma inflammation for predicting phenotypic conversion and clinical progression of autosomal dominant frontotemporal lobar degeneration
Asken, BM, Ljubenkov, PA, Staffaroni, AM, Casaletto, KB, Vandevrede, L, Cobigo, Y, Rojas-Rodriguez, JC, Rankin, KP, Kornak, J, Heuer, H, Shigenaga, J, Appleby, BS, Bozoki, AC, Domoto-Reilly, K, Ghoshal, N, Huey, E, Litvan, I, Masdeu, JC, Mendez, MF, Pascual, B, Pressman, P, Tartaglia, MC, Kremers, W, Forsberg, LK, Boeve, BF, Boxer, AL, Rosen, HJ & Kramer, JH 2023, , Journal of Neurology, Neurosurgery and Psychiatry, vol. 94, no. 7, pp. 541-549. https://doi.org/10.1136/jnnp-2022-330866

Plasma inflammation for predicting phenotypic conversion and clinical progression of autosomal dominant frontotemporal lobar degeneration
ALLFTD Consortium Investigators 2023, , Journal of neurology, neurosurgery, and psychiatry, vol. 94, no. 7, pp. 541-549. https://doi.org/10.1136/jnnp-2022-330866

Feasibility and acceptability of remote smartphone cognitive testing in frontotemporal dementia research
Taylor, JC, Heuer, HW, Clark, AL, Wise, AB, Manoochehri, M, Forsberg, L, Mester, C, Rao, M, Brushaber, D, Kramer, J, Welch, AE, Kornak, J, Kremers, W, Appleby, B, Dickerson, BC, Domoto-Reilly, K, Fields, JA, Ghoshal, N, Graff-Radford, N, Grossman, M, Hall, MGH, Huey, ED, Irwin, D, Lapid, MI, Litvan, I, Mackenzie, IR, Masdeu, JC, Mendez, MF, Nevler, N, Onyike, CU, Pascual, B, Pressman, P, Rankin, KP, Ratnasiri, B, Rojas, JC, Tartaglia, MC, Wong, B, Gorno-Tempini, ML, Boeve, BF, Rosen, HJ, Boxer, AL & Staffaroni, AM 2023, , Alzheimers and Dementia: Diagnosis, Assessment and Disease Monitoring, vol. 15, no. 2, e12423. https://doi.org/10.1002/dad2.12423

Feasibility and acceptability of remote smartphone cognitive testing in frontotemporal dementia research
Taylor, JC, Heuer, HW, Clark, AL, Wise, AB, Manoochehri, M, Forsberg, L, Mester, C, Rao, M, Brushaber, D, Kramer, J, Welch, AE, Kornak, J, Kremers, W, Appleby, B, Dickerson, BC, Domoto-Reilly, K, Fields, JA, Ghoshal, N, Graff-Radford, N, Grossman, M, Hall, MG, Huey, ED, Irwin, D, Lapid, MI, Litvan, I, Mackenzie, IR, Masdeu, JC, Mendez, MF, Nevler, N, Onyike, CU, Pascual, B, Pressman, P, Rankin, KP, Ratnasiri, B, Rojas, JC, Tartaglia, MC, Wong, B, Gorno-Tempini, ML, Boeve, BF, Rosen, HJ, Boxer, AL & Staffaroni, AM 2023, , Alzheimers and Dementia: Diagnosis, Assessment and Disease Monitoring, vol. 15, no. 2, pp. e12423. https://doi.org/10.1002/dad2.12423

Neuroimaging Biomarkers in Alzheimer’s Disease and Related Disorders
Masdeu, JC & Pascual, B 2023, . in Biomarkers in Neuropsychiatry. Springer, Cham, pp. 163-188. https://doi.org/10.1007/978-3-031-43356-6_11

The Self-Administered Screening Questionnaire for Parkinson's Disease-Associated Psychosis (SASPAP)
Koneru, V, Espay, AJ, Cole, AJ, Weintraub, D, Crist, K, Pascual, MB & Ondo, WG 2023, , Movement Disorders, vol. 38, no. 11, pp. 1982-1987. https://doi.org/10.1002/mds.29627

Neuroinflammation co-localizes highly with tau in amnestic mild cognitive impairment
Appleton, J, Funk, Q, Bradbury, K, Yu, M, Faridar, A, Beers, D, Appel, SH, Fujita, M, Masdeu, JC & Pascual, B 2022, , Alzheimers and Dementia, vol. 18, no. S1, e068025. https://doi.org/10.1002/alz.068025

The contribution of behavioral features to caregiver burden in FTLD spectrum disorders
the ALLFTD consortium 2022, , Alzheimers and Dementia, vol. 18, no. 9, pp. 1635-1649. https://doi.org/10.1002/alz.12494

Imaging Neuroinflammation in Neurodegenerative Disorders
Masdeu, JC, Pascual, B & Fujita, M 2022, , Journal of nuclear medicine : official publication, Society of Nuclear Medicine, vol. 63, no. Suppl 1, pp. 45S-52S. https://doi.org/10.2967/jnumed.121.263200

Imaging Neuroinflammation in Neurodegenerative Disorders
Masdeu, JC, Pascual, B & Fujita, M 2022, , Journal of Nuclear Medicine, vol. 63, no. Suppl 1, pp. 45S-52S. https://doi.org/10.2967/JNUMED.121.263200

Comprehensive cross-sectional and longitudinal analyses of plasma neurofilament light across FTD spectrum disorders
Gendron, TF, Heckman, MG, White, LJ, Veire, AM, Pedraza, O, Burch, AR, Bozoki, AC, Dickerson, BC, Domoto-Reilly, K, Foroud, T, Forsberg, LK, Galasko, DR, Ghoshal, N, Graff-Radford, NR, Grossman, M, Heuer, HW, Huey, ED, Hsiung, GYR, Irwin, DJ, Kaufer, DI, Leger, GC, Litvan, I, Masdeu, JC, Mendez, MF, Onyike, CU, Pascual, B, Ritter, A, Roberson, ED, Rojas, JC, Tartaglia, MC, Wszolek, ZK, Rosen, H, Boeve, BF, Boxer, AL & ALLFTD consortium 2022, , Cell Reports Medicine, vol. 3, no. 4, 100607. https://doi.org/10.1016/j.xcrm.2022.100607

Comprehensive cross-sectional and longitudinal analyses of plasma neurofilament light across FTD spectrum disorders
ALLFTD consortium 2022, , Cell Reports Medicine, vol. 3, no. 4, pp. 100607. https://doi.org/10.1016/j.xcrm.2022.100607

Translocator Protein 18 kDa PET Imaging Highlights Asymptomatic Isolated Cerebellar Dysplasia
Pascual, B, Hodics, T, Funk, Q, Cykowski, MD, Nakawah, MO & Masdeu, JC 2022, , Neurology, vol. 98, no. 13, pp. 538-539. https://doi.org/10.1212/WNL.0000000000200221

Proposed research criteria for prodromal behavioural variant frontotemporal dementia
ALLFTD consortium 2022, , Brain, vol. 145, no. 3, pp. 1079-1097. https://doi.org/10.1093/brain/awab365

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