Joseph C. Masdeu, MD, PhD

Joseph C. Masdeu, MD,  PhD

Joseph C. Masdeu, MD, PhD

Memory and Cognitive Disorders Neurology, Neurology
Director, Nantz National Alzheimer Center
Accepting New Patients
Video Visits Available
  • Patient Ratings
  • Publications
  • FAQ

About Dr. Joseph C. Masdeu

Dr. Joseph C. Masdeu is a physician-scientist with expertise in cognitive neurology and neuroimaging. He has published over 150 scientific papers and seven books, most recently two volumes on neuroimaging in the Handbook of Clinical Neurology, a reference work. Under his leadership and thanks to the support of Jim Nantz, the Nantz National Alzheimer Center has become a world‑renowned research and referral center, treating thousands of patients each year, as well as a hub of research to bring better therapeutic approaches for the prevention and treatment of these disorders.

Dr. Joseph C. Masdeu has an academic appointment. Learn more about their research interests.

Clinical Interests

Alzheimer’s disease
Memory disorders
Neuroimaging
Neurodegenerative disorders

Accepted Insurance Plans

  • (WELLMED) AARP MEDICARE ADVANTAGE ESSENTIALS FROM UHC EP-1 (PPO) **
  • (WELLMED) AARP MEDICARE ADVANTAGE EXTRA FROM UHC EP-3 (PPO) **
  • (WELLMED) AARP MEDICARE ADVANTAGE GIVEBACK FROM UHC EP-2 (PPO) **
  • (WELLMED) AARP MEDICARE ADVANTAGE CareFlex FROM UHC TX-44 (HMO-POS)**
  • (WELLMED) AARP MEDICARE ADVANTAGE CareFlex FROM UHC TX-45 (HMO-POS)**
  • (WELLMED) AARP MEDICARE ADVANTAGE ESSENTIAL FROM UHC TX-21 (HMO-POS)**
  • (WELLMED) AARP MEDICARE ADVANTAGE ESSENTIAL FROM UHC TX-22 (HMO-POS)**
  • (WELLMED) AARP MEDICARE ADVANTAGE EXTRA FROM UHC TX-27 (HMO-POS)**
  • (WELLMED) AARP MEDICARE ADVANTAGE EXTRA FROM UHC TX-28 (HMO-POS)**
  • (WELLMED) AARP MEDICARE ADVANTAGE GIVEBACK FROM UHC TX-35 (HMO-POS) **
  • (WELLMED) AARP MEDICARE ADVANTAGE GIVEBACK FROM UHC TX-38(HMO-POS) **
  • (WELLMED) AARP MEDICARE ADVANTAGE GIVEBACK FROM UHC TX-39 (HMO-POS) **
  • (WELLMED) AARP MEDICARE ADVANTAGE GIVEBACK FROM UHC TX-40 (HMO-POS) **
  • (WELLMED) AARP MEDICARE ADVANTAGE GIVEBACK FROM UHC TX-41 (HMO-POS) **
  • (WELLMED) AARP MEDICARE ADVANTAGE GIVEBACK FROM UHC TX-47 (HMO-POS) **
  • (WELLMED) MEDICARE ADVANTAGE GIVEBACK FROM UHC TX-31 (PPO)** H1278-005
  • (WELLMED) MEDICARE ADVANTAGE GIVEBACK FROM UHC TX-31 (PPO)** H1278-013
  • (WELLMED) MEDICARE ADVANTAGE GIVEBACK FROM UHC TX-31 (PPO)** H1278-014
  • (WELLMED) MEDICARE ADVANTAGE GIVEBACK FROM UHC TX-31 (PPO)** H1278-021
  • (WELLMED) MEDICARE ADVANTAGE GIVEBACK FROM UHC TX-31 (PPO)** H1278-025
  • (WELLMED) MEDICARE ADVANTAGE GIVEBACK FROM UHC TX-31 (PPO)** H1278-026
  • (WELLMED) MEDICARE ADVANTAGE GIVEBACK FROM UHC TX-32 (PPO)** H1278-022
  • (WELLMED) MEDICARE ADVANTAGE GIVEBACK FROM UHC TX-34 (PPO)** H1278-024
  • (WELLMED) SECURE HORIZON MEDICARE ADVANTAGE TX-0023 (HMO-POS)**
  • (WELLMED) SECURE HORIZON MEDICARE ADVANTAGE TX-0025 (HMO-POS)**
  • Aetna Affordable Health Choices
  • Aetna APCN Plus Multi-Tier HM Tier 2
  • Aetna Choice POS / Open Choice
  • Aetna Common Spirit Minimum Value Plan
  • Aetna CommonSpirit Health KelseyCare
  • Aetna EPO
  • Aetna Health Network
  • Aetna HMO
  • Aetna International
  • Aetna Managed Choice / Elect Choice
  • Aetna Medicare Advantage HMO
  • Aetna Medicare Advantage PPO
  • Aetna Medicare Dual Complete Plan (HMO D-SNP)
  • Aetna Medicare HMO Prime
  • Aetna Meritain Hlth/Aetna Premier Care (APCN)
  • Aetna Open Access
  • Aetna POS
  • Aetna PPO
  • Aetna Premier Care Network
  • Aetna QPOS
  • Aetna Select
  • Aetna Signature Administrators
  • Aetna Signature Administrators Allied Benefits
  • Aetna Signature Administrators CoreSource
  • Aetna Signature Administrators EBMS
  • Aetna Signature Administrators MODA
  • Aetna Student Health
  • Aetna Transplant
  • Aetna TX Pref Plus II Network
  • Aetna Workers' Comp
  • All Saver/United Healthcare
  • BCBS PPO GUIDESTONE
  • BCBS PPO Wespath
  • Best Doctors International
  • Bind Surest UHC
  • Blue Choice POS
  • Blue Choice PPO
  • Blue Cross Blue Shield EPO
  • Blue Cross Blue Shield FEP Federal Employee Plan
  • Blue Cross Blue Shield Medicare Advantage Out of State
  • Blue Cross Blue Shield Medicare Advantage PPO/UT Care
  • Blue Cross Blue Shield POS
  • Blue Cross Blue Shield PPO
  • Blue Edge
  • Blue Essentials
  • Blue Essentials Access
  • Cigna Allegiance Houston Methodist Employee Medical Plan
  • Cigna Allegiance OAP
  • Cigna Allegiance PPO
  • Cigna APWU
  • Cigna C-24 Network
  • Cigna Choice Fund
  • Cigna EPO
  • Cigna Global Health Benefits (International)
  • Cigna Great West
  • Cigna HMO
  • Cigna Indemnity
  • Cigna LocalPlus
  • Cigna NALC
  • Cigna Network
  • Cigna Network Open Access
  • Cigna Open Access
  • Cigna Open Access Plus (OAP)
  • Cigna POS
  • Cigna PPO
  • Cigna Qualcare
  • Cigna Shared Administration OAP
  • Cigna Shared Administration PPO
  • Cigna SureFit
  • Community Health Choice Medicare Advantage HMO DSNP
  • Community Health Choice PREMIER Gold
  • Community Health Choice PREMIER Silver
  • Coventry PPO
  • DEVOTED CORE 001 TX (HMO)
  • DEVOTED CORE 019 TX (HMO)
  • DEVOTED C-SNP Plus 031 TX (HMO C-SNP)
  • DEVOTED C-SNP Premium 030 TX (HMO C-SNP)
  • DEVOTED DUAL 010 TX (HMO D-SNP)
  • DEVOTED DUAL FULL 040 (HMO D-SNP)
  • DEVOTED GIVEBACK 006 TX (HMO)
  • DEVOTED HEALTH DUAL PLUS GREATER HOUSTON
  • DEVOTED PREMIUM 002 (HMO)
  • Entrust/90 Degree EDI Payer ID# 36878
  • First Health PPO
  • GeoBlue
  • HAA Preferred Partners (International)
  • HealthSmart Accel PPO
  • HealthSmart Payors Organization
  • HealthSmart PPO
  • Healthspring/Cigna MCR HMO
  • Healthspring/Cigna MCR PPO
  • Healthspring/Cigna MCR Total Care Dual
  • HMO Blue
  • Humana Medicare Advantage Choice PPO
  • Humana Medicare Advantage Gold Plus/Choice
  • Humana Medicare Advantage HMO
  • Humana Medicare Advantage PPO
  • Humana TRICARE 2
  • Kelsey Seybold Affiliate Network
  • Medica Choice with UnitedHealthcare Choice Plus
  • Medicare
  • MEDICARE ADVANTAGE : TEXAN PLUS
  • Medicare Railroad
  • Molina Healthcare of TX CHIP MCD
  • Molina Healthcare STAR+PLUS MCD
  • Molina Healthcare TX STAR MCD
  • Molina Marketplace Exchange
  • Molina Medicare Complete Care HMO (Dual) HIDE
  • Molina Medicare Complete Care Plus (HMO Dual-SNP) FIDE
  • MultiPlan PPO
  • Olympus Managed Care (International)
  • PHCS Healthy Directions
  • PHCS MEDI-SHARE
  • PHCS PPO
  • PHCS/Multiplan Practitioner & Ancillary Only
  • ProCare Medicare Advantage
  • Sana Benefits
  • Student Assurance Services Student Accident Plan
  • Texas Kids First /Fidelity Security Student Accident Plan
  • Texas Monarch/Web TPA Student Accident Plan
  • Three Rivers Provider Network
  • TRS-ActiveCare 2 Group 385002
  • TRS-ActiveCare Fully Insured Plan-South Texas Region Group 295430
  • TRS-ActiveCare Fully Insured Plan-West Texas Region Group 295781
  • TRS-ActiveCare HD Group 385000
  • TRS-ActiveCare Primary Group 385003
  • TRS-ActiveCare Primary Plus Group 385001
  • TRS-Care Standard ALT A I Group 485002
  • TRS-Care Standard ALT A II Group 485003
  • TRS-Care Standard ALT B I Group 485005
  • TRS-Care Standard ALT B II Group 485006
  • TRS-Care Standard CMED Group 485001
  • TRS-Care Standard Group 485000
  • TX Annual Conf of UMC-UMR
  • UHC COMPLETE CARE SUPPORT TX-1A (REGIONAL PPO C-SNP)** R6801-008
  • UHC Complete Care TX-16 (HMO-POS C-SNP)** H4527-039
  • UHC Complete Care TX-17 (HMO-POS C-SNP)** H4527-040
  • UHC Complete Care TX-18 (HMO-POS C-SNP)** H4527-041
  • UHC Complete Care TX-19 (HMO-POS C-SNP)** H4527-042
  • UHC COMPLETE CARE TX-29 (REGIONAL PPO C-SNP)** R6801-009
  • UHC DUAL COMPLETE TX-S001 (REGIONAL PPO D-SNP)** R6801-011
  • UHC GR MA HALLIBURTON HMO 137 ** H0609-822-137
  • UHC GR MA LOCKHEED HMO 164 ** H0609-822-164
  • UHC GR MA RIO TINTO SERVICE
  • UHC GR MA TEACHER RETIREMENT SYSTEM HMO 199** H0609-822-207
  • UHC GR MA VERIZON HMO 207** H0609-822-207
  • UHC MEDICARE ADVANTAGE TX-0030 (REGIONAL PPO)** R6801-012
  • UMR
  • United Health Integrated Services
  • United HealthCare Community Plan Dual Complete (HMO SNP)
  • United Healthcare Nexus ACO RA or OA
  • United Healthcare Plan of the River Valley
  • UnitedHealthcare Choice
  • UnitedHealthcare ChoicePlus
  • UnitedHealthcare Core
  • UnitedHealthcare Core Plus
  • UnitedHealthcare EPO
  • UnitedHealthcare Golden Rule
  • UnitedHealthcare HMO
  • UnitedHealthcare Navigate
  • UnitedHealthcare Navigate Plus
  • UnitedHealthcare Options PPO
  • UnitedHealthcare Oxford
  • UnitedHealthcare POS
  • UnitedHealthcare PPO
  • UnitedHealthcare Student Resources
  • UnitedHealthcare West
  • UnitedHealthOne
  • US Family Health Plan
  • WellMed AARP Medicare Advantage Choice PPO
  • WellMed AARP Medicare Advantage Plan 1 & Plan 2
  • WellMed Medicare Advantage Choice PPO
  • WellMed Medicare Advantage Patriot
  • WellMed UHC Dual Complete HMO D-SNP
  • WellMed UnitedHealthCare Dual Complete Choice (Regional PPO D-SNP)
  • WellMed UnitedHealthCare Medicare Advantage Choice (Regional PPO)
  • WellMed UnitedHealthCare Medicare Gold (Regional PPO C-SNP)
  • WellMed UnitedHealthCare Medicare Silver (Regional PPO C-SNP)
  • Wellpoint Chronic Care (HMO C-SNP)
  • Wellpoint Dual Advantage (HMO D-SNP)
  • Wellpoint Dual Advantage 2 (HMO D-SNP)
  • WELLPOINT ESSENTIALS MARKETPLACE
  • Wellpoint Full Dual Advantage (HMO D-SNP)
  • Wellpoint Full Dual Advantage 2 (HMO D-SNP)
  • Wellpoint Home Care (HMO C-SNP)
  • Wellpoint Kidney Care (HMO C-SNP)
  • Wellpoint Kidney Care (HMO-POS C-SNP)
  • Wellpoint Lung Care (HMO C-SNP)
  • Wellpoint Medicare Advantage 2 (HMO)
  • Wellpoint Select (HMO)
Insurance plans may change. Please verify your plan is accepted when scheduling an appointment.

Credentials

Board Certification
  • American Board of Psychiatry and Neurology, Neurology
  • Neuroimaging | The United Council for Neurological Subspecialties
Medical School
  • Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain | 1969
Internship
  • Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain
Residency
  • Neurology, Mount Sinai Hospital, Chicago, Illinois
Affiliated Hospitals
  • Houston Methodist Hospital
Center Memberships
  • Houston Methodist Neurological Institute
Academic Appointments
  • Graham Family Distinguished Chair for Neurological Sciences, Stanley H. Appel Department of Neurology
  • Professor of Neurology, Academic Institute
  • Member, Research Institute, Academic Institute
  • Program Director, Behavioral Neurology and Neuropsychiatry Fellowship, Stanley H. Appel Department of Neurology
  • Director, Nantz National Alzheimer Center
  • Houston Methodist
  • Weill Cornell Medical College

Languages

  • English
  • Spanish
Languages listed are spoken by doctor and/or office staff.

FAQ

Can I book an appointment with Dr. Joseph C. Masdeu?
Yes. Please contact the physician's office directly at 713.441.1150 to schedule an appointment or call 713.790.3333 for assistance in finding another doctor.
What insurance does Dr. Joseph C. Masdeu accept?
See all insurance plans that Dr. Joseph C. Masdeu accepts.
What practice does Dr. Joseph C. Masdeu work at?
Dr. Joseph C. Masdeu works at Houston Methodist Stanley H. Appel Department of Neurology.
Where is Dr. Joseph C. Masdeu office located?
How do patients rate Dr. Joseph C. Masdeu in reviews?
220 patients have reviewed Dr. Joseph C. Masdeu. The overall rating for this doctor is 4.9/5. You can read individual reviews and ratings on Dr. Joseph C. Masdeu's profile.
What languages does Dr. Joseph C. Masdeu speak?
Dr. Joseph C. Masdeu, or the office, speaks English, Spanish.
What are Dr. Joseph C. Masdeu's specialties?
Dr. Joseph C. Masdeu is a specialist in Memory and Cognitive Disorders Neurology, Neurology.

Patient Ratings & Comments

What is a Patient Rating score?
The Patient Rating score is an average of all responses to physician related questions on our independently administered Patient Satisfaction Survey.
How are responses measured?
Responses are measured on a scale of 1 to 5, with 5 being the best score.
4.9 out of 5
(220 Ratings, 33 Comments)
  • 4.9
    Provider discussed treatment options
  • 4.9
    Provider showed concern
  • 4.9
    Provider explained things clearly
  • 4.9
    Provider included you in decisions
  • 4.9
    Likelihood of recommending this provider
Comments also are gathered from our Patient Satisfaction Survey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.
  • Sep 1, 2026
    Dr Masdeu was excellent. Examined me thoroughly after taking a detailed history and then explained everything in detail including my scans afterwards and then discussed his treatment recommendations in great detail explaining everything about the treatment including how the medication worked, the risks etc.
  • Sep 1, 2026
    Very pleased with this visit!
  • Jul 21, 2026
    After visit communication was so compassionate and timely.
  • Jun 22, 2026
    All was clear and up-to-date considering this field is rapidly evolving. Dr. Masdeu has one of the few approved treatments for Alzheimers and I was eager to learn more. He and his staff were efficient in determining my status for this therapy.
  • Jun 16, 2026
    Simply the best!!!
  • Jun 9, 2026
    Verify knowledgeable and explained everything
  • May 29, 2026
    Dr. Masdeu is a very detailed, experienced, caring and outstanding Neurologist.