Types and Causes of Blood Cancer
Leukemia is cancer of the blood or bone marrow. It includes four main types:
- Acute lymphoblastic leukemia (ALL)
- Acute myeloid leukemia (AML)
- Chronic lymphocytic leukemia (CLL)
- Chronic myeloid leukemia (CML)
Leukemia occurs due to excessive production of abnormal white blood cells in the bone marrow. This limits the ability of the bone marrow to produce enough red blood cells (which carry oxygen and remove carbon dioxide) and platelets (needed for blood clotting).
Lymphoma is a blood cancer that affects the lymphatic system — tissues, organs, glands (lymph nodes) and vessels that collect and filter excess fluid (called lymph) and return it back into the bloodstream as plasma. As part of the immune system, the lymphatic system also produces white blood cells.
Lymphoma includes two main types: Hodgkin’s lymphoma and non-Hodgkin’s lymphoma.
Lymphoma occurs when abnormal white blood cells grow out of control, eventually accumulating to levels that negatively affect the function of your lymph nodes, spleen and liver.
Myeloma occurs when plasma cells (antibody-producing white blood cells) in the bone marrow become abnormal and grow uncontrollably. Their growth limits the ability for bone marrow to produce healthy blood cells and platelets.
Abnormal plasma cells don't produce functional antibodies. Instead, they produce nonfunctional antibodies that cause issues as their levels expand.
Nationally Ranked for Cancer Care
Houston Methodist Hospital is nationally ranked by U.S. News & World Report for cancer. In addition, we are considered high performing by U.S. News & World Report for leukemia, lymphoma and myeloma.
Why Choose Houston Methodist for Blood Cancer Treatment
Hematologists, oncologists and other specialists work together to develop a personalized treatment plan tailored to your needs. We use advanced diagnostics and treatment options — including molecular testing, immunotherapy and stem cell transplant — to stop your cancer as quickly and safely as possible.
Our pioneering research and clinical trials result in new therapies developed to combat cancer. Houston Methodist patients may access clinical trials offering potentially promising treatments not available to the public.
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Leukemia, Lymphoma & Myeloma FAQs
How common is blood cancer?
Is blood cancer curable?
Yes, blood cancer can be curable, depending on the type and how soon you receive treatment. Early diagnosis can improve your treatment options and outcomes.
Certain blood cancers are uncurable, such as chronic lymphocytic leukemia, chronic myeloid leukemia and myeloma. If a cancer is not curable, the focus is on treating the condition and putting it into remission (reduced or eliminated symptoms).
Survival rates vary, depending on your overall health, age and response to treatment. According to the National Cancer Institute, the five-year relative survival rate (percentage of people alive five years after diagnosis) is:
- Leukemia – 67%
- Non-Hodgkin lymphoma – 74%
- Hodgkin lymphoma – 89%
- Myeloma – 61%
Why are early screening tests not available for blood cancer?
There are no early screening tests available for blood cancers like leukemia, lymphoma or myeloma due to these factors:
- the complexity and variability of these diseases
- the diverse types and presentations of blood cancers
- the lack of universally accepted biomarkers for early detection
Unlike some solid tumors, such as breast cancer or prostate cancer, blood cancers have multiple subtypes with varying characteristics and progression patterns. This makes it challenging to develop a one-size-fits-all screening test.
There is an absence of reliable and specific biomarkers. Current biomarkers are useful to monitor disease progression and response to treatment, though not for early detection.
How can I reduce my risk of developing blood cancer?
Attend regular medical checkups and consultations with your health care provider for personalized risk assessments and prevention tactics.
Is blood cancer contagious?