Clinical Translation & Trials

 

At Houston Methodist, our deep commitment to finding new ways to prevent and treat illness so as to improve the health of our patients means that our primary goal is to make a clinical trial available to every person who needs and wants to participate in one. Houston Methodist monitors more than 300 clinical protocols; while not all of them are actively enrolling patients at this time, many are, with new ones being opened every month.

1,690

Clinical Studies & Trials in 2023

2,340

Credentialed Researchers

2,000

Peer-Reviewed Publications in 2023
The Cockrell Centers for Advanced Therapeutics are located throughout the greater Houston metro area. They provide services, staffing and facilities to physicians for conducting internally and externally sponsored clinical research close to their practices. The Cockrell Centers also offer a Clinical Research Phase 1 Unit located in the Texas Medical Center that can conduct advanced pharmacokinetic or pharmacodynamic evaluations for early-phase and proof-of-concept clinical trials.

Our clinical research services for physicians and research investigators include:
  • Research outpatient services
  • Regulatory and budget management
  • Private rooms for infusion
  • Fully equipped specimen processing laboratory
  • Adjacent state-of-the-art inpatient services, including critical care monitoring
  • Secure storage, preparation, and dispensing services for investigational products with 24/7 temperature monitoring
  • Pharmacokinetic and pharmacodynamic sampling (extended hours)

Research and Clinical Trial Highlights

Engaging T cell Exhaustion for Solid Tumor Immunotherapies
Houston Methodist researchers investigated T cell exhaustion in murine models of prostate cancer and melanoma to explore possible advancements in immunotherapies for solid tumors.
Open Clinical Trial: Endometrial Cancer
Determine the value for patients of sentinel node biopsy compared to no-node dissection in endometrial cancer.
Evolving Treatment Beyond Pharmaceuticals
First-of-its-Kind Study Explores Novel Prescription Digital Therapeutic
Open Clinical Trial: Endometrial Cancer
Selinexor in maintenance therapy after systemic therapy for patients with p53 wild-type, advanced or recurrent endometrial carcinoma.
Diabetics Pay a Higher Price for Health Inequities
Cumulative social disadvantage in diabetics is associated with significantly increased mortality risk, beyond established risk factors.
Open Clinical Trial: LANCE Trial – Ovarian Cancer
Minimally invasive surgery after neoadjuvant chemotherapy for treatment of Stage IIIC-IV ovarian, primary peritoneal or fallopian tube cancer.
Knee Surgery Goes Pro
To investigate osteochondral allograft outcomes in the specific population of high-level professional athletes, Sachin Allahabadi, MD, Assistant Professor of Clinical Orthopedic Surgery at Houston Methodist, published a recent study.
Open Clinical Trial: Endometrial Cancer
Compare the efficacy and safety of MK-2870 monotherapy versus treatment of physician's choice in participants with endometrial cancer who have received prior platinum-based chemotherapy and immunotherapy.
A New Age of Wound Care
Treating wounds with telomerase mRNA in a lipid nanoparticle counteracts telomere shortening to improve wound healing.
Groundbreaking ALS Study Offers New Insight

Houston Methodist researchers have identified a key player and mechanism involved in the development of ALS, a promising discovery that could open the door for future therapeutic interventions.

Find a Clinical Trial

I am interested in
Blood and Lymph Conditions
  • Blood and Lymph Conditions
  • Cancers and Other Neoplasms
  • Digestive System Diseases
  • Diseases and Abnormalities at or before Birth
  • Gland and Hormone Related Diseases
  • Heart and Blood Diseases
  • Immune System Diseases
  • Muscle, Bone, and Cartilage Diseases & Disorders
  • Nervous System Diseases & Disorders
  • Nutritional and Metabolic Conditions & Diseases
  • Other
  • Respiratory Tract (Lung and Bronchial) Diseases
  • Skin and Connective Tissue Diseases
  • Symptoms and General Pathology
  • Transplant Trials
  • Urinary Tract, Sexual Organs, and Pregnancy Conditions
  • Viral Diseases

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Questions About Clinical Trials?

Contact Us: 713.441.3250