Publications


HDL-Free Cholesterol Influx into Macrophages and Transfer to LDL Correlate with HDL-Free Cholesterol Content;
Yelamanchili, D, Gillard, BK, Gotto, AM, Achirica, MC, Nasir, K, Remaley, AT, Rosales, C & Pownall, HJ 2025, , Journal of lipid research, pp. 100707. https://doi.org/10.1016/j.jlr.2024.100707

Carvedilol suppresses ryanodine receptor-dependent Ca2+ bursts in human neurons bearing PSEN1 variants found in early onset Alzheimer’s disease;
Hori, A, Inaba, H, Hato, T, Tanaka, K, Sato, S, Okamoto, M, Horiuchi, Y, Paran, FJ, Tabe, Y, Mori, S, Rosales, C, Akamatsu, W, Murayama, T, Kurebayashi, N, Sakurai, T, Ai, T & Miida, T 2024, , PLoS ONE, vol. 19, no. 8 August, e0291887. https://doi.org/10.1371/journal.pone.0291887

A phase 1 proof-of-concept study evaluating safety, tolerability, and biological marker responses with combination therapy of CTLA4-Ig and interleukin-2 in amyotrophic lateral sclerosis;
Thonhoff, JR, Beers, D, Zhao, W, Faridar, A, Thome, AD, Wen, S, Zhang, A, Wang, J & Appel, SH 2024, , Frontiers in Neurology, vol. 15, pp. 1415106. https://doi.org/10.3389/fneur.2024.1415106

RELATIVE COMPLEX I and II SOURCED ROS IN HUMAN PROSTATE CANCER;
Zhang, A, Hankins, S, Vedula, I, Ayala, A, Miles, BJ & Hamilton, DJ 2024, , Department of Medicine Annual Celebration Poster Session, Houston, United States, 4/24/24.

FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease;
Kodavati, M, Wang, H, Guo, W, Mitra, J, Hegde, PM, Provasek, V, Rao, VHM, Vedula, I, Zhang, A, Mitra, S, Tomkinson, AE, Hamilton, DJ, Van Den Bosch, L & Hegde, ML 2024, , Nature Communications, vol. 15, no. 1, 2156. https://doi.org/10.1038/s41467-024-45978-6

FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease;
Kodavati, M, Wang, H, Guo, W, Mitra, J, Hegde, PM, Provasek, VE, Maloji Rao, VH, Vedula, I, Zhang, A, Mitra, S, Tomkinson, AE, Hamilton, DJ, Van Den Bosch, L & Hegde, M 2024, , Nat Commun, vol. 15, no. 1, pp. 2156. https://doi.org/10.1038/s41467-024-45978-6

Long-term sustained effects of the Look AHEAD lifestyle intervention on body composition among adults with type 2 diabetes;
Ashby-Thompson, M, Heshka, S, Anderson, A, Pownall, H, Laferrère, B, Balasubramanyam, A, Heymsfield, SB, Wadden, TA & Gallagher, D 2024, , Obesity, vol. 32, no. 6, pp. 1093-1101. https://doi.org/10.1002/oby.24025

A phase 1 proof-of-concept study evaluating safety, tolerability, and biological marker responses with combination therapy of CTLA4-Ig and interleukin-2 in amyotrophic lateral sclerosis;
Thonhoff, JR, Beers, DR, Zhao, W, Faridar, A, Thome, A, Wen, S, Zhang, A, Wang, J & Appel, SH 2024, , Frontiers in Neurology, vol. 15, 1415106, pp. 1415106. https://doi.org/10.3389/fneur.2024.1415106

The pathophysiology of excess plasma-free cholesterol;
Gillard, BK, Rosales, C, Gotto, AM & Pownall, HJ 2023, , Current opinion in lipidology, vol. 34, no. 6, pp. 278-286. https://doi.org/10.1097/MOL.0000000000000899

The pathophysiology of excess plasma-free cholesterol;
Gillard, BK, Rosales, C, Gotto, AM & Pownall, HJ 2023, , Current opinion in lipidology, vol. 34, no. 6, PMID: 37732779, pp. 278-286. https://doi.org/10.1097/MOL.0000000000000899, https://doi.org/10.1097/MOL.0000000000000899